At the system level, our research build innovative hardware and software systems in medical imaging and radiotherapy to improve precision, efficiency, and quality in patient care. 

On the hardware front, we are developing systems designed to enhance image resolution, guidance, and treatment delivery. Our projects include an ultra-high-resolution CT scanner, an ultra-low-field MRI for image-guided radiotherapy, and a small-animal irradiator that integrates spectral CT, PET, and MRI for precise image guidance and intensity-modulated radiation delivery. On the software side, one of our notable developments is the AutoBrachy system, designed to improve the planning and quality assurance of high-dose-rate brachytherapy (HDRBT) for gynecological cancer. Traditionally, HDRBT treatment planning is performed manually under high time pressure, which can lead to variability in plan quality and increase the potential for error based on the planner’s experience level. AutoBrachy overcomes these challenges by using advanced image processing techniques to segment anatomical structures and applicators, allowing for automatic treatment planning in just a few minutes.  

Funding Support:
  1. “Next generation small animal radiation research platform.”NIH/NCI, R37CA214639, 02/2018 – 09/2025. 
  2. “Low-cost Non-conventional Ultra-low-field MRI Scanner For the Next-Generation MR-guided Radiation Therapy.” High Impact/High Risk aware. Cancer Prevention and Research Institute of Texas, RP200573, 08/2020 – 07/2022.
  3. “Next generation high dose-rate brachytherapy treatment planning for gynecological cancer,” Varian Master Research Agreement, 12/2015 – 11/2018.